Atlético de Madrid and Union Saint-Gilloise will meet for the first time here; the Spanish side have only won two of their previous six games against Belgian sides in the European Cup/UEFA Champions League (D2 L2), and are winless in the last three (D2 L1).

Atlético de Madrid have failed to score in three consecutive matches against Belgian teams in the UEFA Champions League, all of which were against Club Brugge between December 2018 and October 2022 (D2 L1).

This will be the 23rd time that a Belgian team have faced a Spanish opponent away from home in the European Cup/UEFA Champions League, while they have won just two of the previous 22 (D6 L14). The last side to do so were Anderlecht in December 2005, winning 1-0 away at Real Betis (D3 L4 since then).

Atlético de Madrid have lost two of their three UEFA Champions League group games this season, as many as they lost in 2023-24 and 2024-25 combined (W10 D2 L2). They last suffered three group defeats in 2022-23.

After winning their first UEFA Champions League match 3-1 against PSV, Union Saint-Gilloise have lost their last two both 4-0, against Newcastle and Internazionale. Only two teams have lost by 4+ goals without scoring in three Champions League games in a row – Malmö FF in November/December 2015 and Crvena Zvezda in October/November 2019.

Atlético de Madrid are unbeaten in their last 16 home UEFA Champions League matches against sides from a nation outside of Europe’s big-five leagues (W11 D5), with their last five home defeats coming against sides from England (3), Italy (1) and France (1) since a 2-1 defeat to Benfica in September 2015.

Although they’ve lost their two home UEFA Champions League games, Union Saint-Gilloise won their first away game 3-1 at PSV. Only five teams have won their first two away games in the competition – most recently Brest last season – and no side has ever lost their first two home games but won their first two on the road.

Union Saint-Gilloise’s Kevin Mac Allister has scored in each of his last three away major European appearances, including his only away UEFA Champions League appearance. The only Argentinian to score in his first two away games in the competition is Julio Rossi in 2002 for Basel.

Antoine Griezmann’s next UEFA Champions League appearance will be his 109th, moving ahead of Patrice Evra (108) into the outright third spot for most games played by a Frenchman in the competition. He’s had a hand in 37 goals in 43 home appearances for Atlético de Madrid (28 goals, 9 assists), including 12 in his last 12 on home soil (9 goals, 3 assists).

Between spells at Manchester City and his current club Atlético de Madrid, Julián Alvarez has been directly involved in 15 goals in 10 home matches he has started in the UEFA Champions League (10 goals, five assists). Across those 10 starts, he has averaged a goal or assist every 59 minutes played.